MercoPress, en Español

Montevideo, October 19th 2018 - 03:13 UTC

Nobel Medicine Prize for harnessing immune system to fight cancer

Tuesday, October 2nd 2018 - 08:43 UTC
Full article
“Allison and Honjo showed how different strategies for inhibiting the brakes on the immune system can be used in the treatment of cancer” “Allison and Honjo showed how different strategies for inhibiting the brakes on the immune system can be used in the treatment of cancer”
James Allison, professor at the University of Texas MD Anderson Cancer Center, studied a protein that functions as a brake on the immune system James Allison, professor at the University of Texas MD Anderson Cancer Center, studied a protein that functions as a brake on the immune system
Tasuku Honjo, professor at Kyoto University since 1984, separately discovered a second protein on immune cells and revealed that it too operated as a brake Tasuku Honjo, professor at Kyoto University since 1984, separately discovered a second protein on immune cells and revealed that it too operated as a brake

James Allison from the United States and Japanese Tasuku Honjo won the 2018 Nobel Prize for Medicine for discoveries leading to new approaches in harnessing the immune system to fight cancer, the award-giving body said on Monday.

“Allison and Honjo showed how different strategies for inhibiting the brakes on the immune system can be used in the treatment of cancer,” the Nobel Assembly at Sweden’s Karolinska Institute said, on awarding the prize of 9 million Swedish crowns (€870,000).

Medicine is the first of the Nobel Prizes awarded each year. The prizes for achievements in science, literature and peace were created in accordance with the will of dynamite inventor and businessman Alfred Nobel and have been awarded since 1901.

The literature prize will not be handed out this year after the awarding body was hit by a sexual misconduct scandal.

Both laureates studied proteins that prevent the body and its main immune cells, known as T-cells, from attacking tumor cells effectively.

Mr Allison, professor at the University of Texas MD Anderson Cancer Center, studied a protein that functions as a brake on the immune system and realized the potential for unleashing immune cells to attack tumors if the brake could be released.

Mr Honjo, professor at Kyoto University since 1984, separately discovered a second protein on immune cells and revealed that it too operated as a brake, but with a different mechanism.

“The seminal discoveries by the two Laureates constitute a landmark in our fight against cancer,” the institute said.

Top Comments

Disclaimer & comment rules

Commenting for this story is now closed.
If you have a Facebook account, become a fan and comment on our Facebook Page!